Achieve dramatic weight loss with Retatrutide (Triple G), a cutting-edge therapy that targets three key metabolic pathways for unparalleled results. Formulated to curb appetite, regulate blood sugar, and boost calorie burning, this next-generation treatment may deliver up to 24% body weight reduction, outperforming existing GLP-1 medications in clinical trials.
Lose up to a quarter of your weight with the 3 Gs
Triple G – Retatrutide is a weight loss medication that combines the power of three hormone receptors (GIP, GLP‑1, and glucagon) into one treatment. By suppressing appetite, improving insulin sensitivity, and increasing energy expenditure, it delivers comprehensive metabolic support. Early clinical trials show it may help patients lose up to 24% of their body weight, significantly more than existing options like semaglutide or tirzepatide.
Triple G - Retatrutide helps with:
- Excess body weight in individuals with obesity
- Weight-related complications in type 2 diabetes
- Insulin resistance and poor glycemic control
- Fat accumulation in the liver
- Slow metabolic rate and low energy expenditure
The working of Triple G - Retatrutide
Triple G – Retatrutide is a triple hormone receptor agonist that activates GIP, GLP‑1, and glucagon receptors simultaneously. This multifaceted approach delivers powerful metabolic benefits by targeting appetite regulation, glucose control, and energy expenditure. By engaging all three hormonal pathways, Retatrutide addresses multiple causes of obesity and metabolic dysfunction, making it one of the most promising treatments for weight loss.
GIP
Glucose-dependent insulinotropic polypeptide (GIP) plays a vital role in enhancing insulin secretion in response to food intake. In Retatrutide, GIP receptor activation supports blood sugar control while also contributing to improved insulin sensitivity and metabolic function. While GIP alone is not highly effective for weight loss, in combination with GLP-1 and glucagon, it helps balance the overall hormonal response and enhances the therapeutic effect.
GLP-1
Glucagon-like peptide-1 (GLP‑1) is widely known for its ability to suppress appetite and slow gastric emptying, which helps individuals feel fuller faster. This enables you to maintain a low-calorie diet more easily and achieve sustainable weight loss. It also supports insulin production and inhibits glucagon release, which stabilizes blood sugar levels. Retatrutide’s GLP‑1 activity contributes significantly to reduced calorie intake and long-term weight management.
Glucagon
Glucagon receptor activation is what sets Retatrutide apart from both semaglutide and tirzepatide. While glucagon typically raises blood sugar, in a therapeutic setting, its controlled stimulation increases energy expenditure and fat oxidation. This process supports additional weight reduction by accelerating the body’s natural calorie-burning capacity, making Retatrutide a unique and comprehensive solution for long-term weight management.
Benefits of Triple G - Retatrutide:
- Delivers industry-leading weight loss results
- Targets three metabolic pathways simultaneously
- Reduces appetite and increases satiety
- Enhances insulin sensitivity and glucose control
- Boosts energy expenditure and fat metabolism
- May significantly reduce liver fat in patients with MASLD
- Outperforms semaglutide and tirzepatide in trials
- Supports long-term metabolic health and body composition
Triple G - Retatrutide FAQs
How much weight can I expect to lose?
In clinical studies, participants taking the highest dose of Retatrutide lost an average of 17.5% of their body weight in just 24 weeks, and up to 24.2% at 48 weeks. That’s a substantial reduction, and it outperforms today’s leading medications. For comparison, semaglutide typically leads to about 14 to 15% weight loss, and tirzepatide results in around 20% weight loss.
What are the side effects?
The most common side effects are mild to moderate and include nausea, vomiting, diarrhea, and constipation. These symptoms often improve with time or with dose adjustments. Some people may also experience a slight increase in heart rate.
How is Retatrutide taken?
Like other GLP‑1-based medications, Retatrutide is given as a once-weekly subcutaneous injection. The dose is usually increased gradually to help minimize side effects.
Schedule your consultation
Aesthetic Envy is proud to stay at the forefront of transformative weight loss solutions, including the groundbreaking Triple G – Retatrutide. Our expert team, led by certified master injector Dr. Kasturi, takes an innovative, personalized approach to help you achieve lasting results. If you’re ready to explore one of the most advanced options in metabolic health and body transformation, schedule your consultation today to see if Retatrutide is right for you.
